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Pre-existing type-2 diabetes is not an adverse prognostic factor in patients with renal cell carcinoma: A single-center retrospective study
27 January 2012
Alessandro Antonelli, Nicola Arrighi, Serena Corti, Tiziano Zanotelli, Alberto Cozzoli, Sergio Cosciani Cunico, Claudio Simeone
Abstract: Objectives: Type-2 diabetes mellitus (DM) is a metabolic disease affecting several million people all over the world. The correlation between DM and malignancies is well established due to t...
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Risk of renal cell carcinoma and polymorphism in phase I xenobiotic metabolizing CYP1A1 and CYP2D6 enzymes
27 January 2012
Shiekh Tanveer Ahmad, Wani Arjumand, Amlesh Seth, Sana Nafees, Summya Rashid, Nemat Ali, Oday O. Hamiza, Sarwat Sultana
Abstract: The progressive increase in sporadic renal cell carcinoma (RCC) observed in industrialized countries supports the opinion that certain carcinogens present in the environment (tobacco smoke, ...
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Patterns of autophagy in urothelial cell carcinomas—the significance of “stone-like” structures (SLS) in transurethral resection biopsies
27 January 2012
Efthimios Sivridis, Michael I. Koukourakis, Savvas E. Mendrinos, Stavros Touloupidis, Alexandra Giatromanolaki
Abstract: 0bjectives: To investigate the microtubule-associated protein LC3A, presumed to reflect autophagic activity, in urothelial cell carcinomas (UCC) for its relevance with muscle invasion in tra...
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The prostate cancer-up-regulated long noncoding RNA PlncRNA-1 modulates apoptosis and proliferation through reciprocal regulation of androgen receptor
24 January 2012
Zilian Cui, Shancheng Ren, Ji Lu, Fubo Wang, Weidong Xu, Yi Sun, Min Wei, Junyi Chen, Xu Gao, Chuanliang Xu, Jian-Hua Mao, Yinghao Sun
Abstract: Objective: Emerging evidences implicate long noncoding RNAs (lncRNAs) are deregulated in cancer development. The purpose of the current study is to investigate the role of new lncRNA, named ...
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Adjuvant and neoadjuvant therapy for renal cell carcinoma: A survey of the Society of Urologic Oncology
24 January 2012
Conrad M. Tobert, Robert G. Uzzo, Christopher G. Wood, Brian R. Lane
Abstract: Objective: Several systemic agents have been approved for patients with advanced renal cell carcinoma (RCC) and others are in various stages of development. We surveyed members of the Societ...
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