Urologic Oncology: Seminars and Original Investigations
Volume 24, Issue 5 , Pages 384-390 , September 2006

Treatment of intermediate-risk prostate cancer with brachytherapy without supplemental pelvic radiotherapy: A review of the H. Lee Moffitt Cancer Center experience

Presented at the 46th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Atlanta, GA, October 3–7, 2004.

  • Javier F. Torres-Roca, M.D.

      Affiliations

    • Department of Interdisciplinary Oncology, University of South Florida College of Medicine and H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-813-972-8424; fax: +1-813-979-7231.
  • ,
  • Alan B. Cantor, Ph.D.

      Affiliations

    • Department of Interdisciplinary Oncology, University of South Florida College of Medicine and H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
  • ,
  • Sonia Shukla

      Affiliations

    • Department of Interdisciplinary Oncology, University of South Florida College of Medicine and H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
  • ,
  • Michael E. Montejo, B.S.

      Affiliations

    • Department of Interdisciplinary Oncology, University of South Florida College of Medicine and H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
  • ,
  • Jay Friedland, M.D.

      Affiliations

    • Department of Interdisciplinary Oncology, University of South Florida College of Medicine and H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
  • ,
  • John D. Seigne, M.B.

      Affiliations

    • Section of Urology, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA
  • ,
  • Randy Heysek, M.D.

      Affiliations

    • Department of Interdisciplinary Oncology, University of South Florida College of Medicine and H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
  • ,
  • Julio Pow-Sang, M.D.

      Affiliations

    • Department of Interdisciplinary Oncology, University of South Florida College of Medicine and H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA

Received 27 June 2005 ,Revised 16 December 2005 ,Accepted 22 December 2005.

References 

  1. Quaranta BP , Marks LB , Anscher MS . Comparing radical prostatectomy and brachytherapy for localized prostate cancer . Oncology (Huntingt) . 2004;18:1289–1302
  2. Partin AW , Kattan MW , Subong EN , et al.   Combination of prostate-specific antigen, clinical stage, and Gleason score to predict pathological stage of localized prostate cancer (A multi-institutional update) . JAMA . 1997;277:1445–1451
  3. Critz FA , Williams WH , Levinson AK , et al.   Simultaneous irradiation for prostate cancer: Intermediate results with modern techniques . J Urol . 2000;164:738–741
  4. Dattoli M , Wallner K , True L , et al.   Long-term outcomes after treatment with external beam radiation therapy and palladium 103 for patients with higher risk prostate carcinoma: Influence of prostatic acid phosphatase . Cancer . 2003;97:979–983
  5. Lederman GS , Cavanagh W , Albert PS , et al.   Retrospective stratification of a consecutive cohort of prostate cancer patients treated with a combined regimen of external-beam radiotherapy and brachytherapy . Int J Radiat Oncol Biol Phys . 2001;49:1297–1303
  6. Sylvester JE , Blasko JC , Grimm PD , et al.   Ten-year biochemical relapse-free survival after external beam radiation and brachytherapy for localized prostate cancer: The Seattle experience . Int J Radiat Oncol Biol Phys . 2003;57:944–952
  7. Davis BJ , Haddock MG , Wilson TM , et al.   Treatment of extraprostatic cancer in clinically organ-confined prostate cancer by permanent interstitial brachytherapy: Is extraprostatic seed placement necessary? . Tech Urol . 2000;6:70–77
  8. Sohayda C , Kupelian PA , Levin HS , et al.   Extent of extracapsular extension in localized prostate cancer . Urology . 2000;55:382–386
  9. Sarosdy MF . Urinary and rectal complications of contemporary permanent transperineal brachytherapy for prostate carcinoma with or without external beam radiation therapy . Cancer . 2004;101:754–760
  10. Speight JL , Elkin EP , Pasta DJ , et al.   Longitudinal assessment of changes in sexual function and bother in patients treated with external beam radiotherapy or brachytherapy, with and without neoadjuvant androgen ablation: Data from CaPSURE . Int J Radiat Oncol Biol Phys . 2004;60:1066–1075
  11. Brandeis J , Pashos CL , Henning JM , et al.   A nationwide charge comparison of the principal treatments for early stage prostate carcinoma . Cancer . 2000;89:1792–1799
  12. Cox JD , Grignon DJ , Kaplan RS  American Society for Therapeutic Radiology and Oncology Consensus Panel . Consensus statement: Guidelines for PSA following radiation therapy . Int J Radiat Oncol Biol Phys . 1997;37:1035–1041
  13. American Joint Committee on Cancer American Cancer Society American College of Surgeons . AJCC cancer staging manual . 5th ed.. Philadelphia (PA): Lippincott-Raven; 1997;
  14. Kaplan EL , Meier PL . Nonparametric estimation from incomplete observations . J Am Stat Assoc . 1958;53:457–481
  15. Greenwood M . The natural duration of cancer . Rep Public Health Med Subj (Lond) . 1926;33:1–26
  16. Mantel N . Evaluation of survival data and 2wo new rank order statistics arising in its consideration . Cancer Chemother Rep . 1966;50:163–170
  17. Merrick GS , Butler WM , Galbreath RW , et al.   Perineural invasion is not predictive of biochemical outcome following prostate brachytherapy . Cancer J . 2001;7:404–412
  18. Grann A , Gaudin PB , Raben A , et al.   Pathologic features from prostate needle biopsy and prognosis after I-125 brachytherapy . Radiat Oncol Investig . 1998;6:170–174
  19. Anderson PR , Hanlon AL , Patchefsky A , et al.   Perineural invasion and Gleason 7–10 tumors predict increased failure in prostate cancer patients with pretreatment PSA <10 ng/ml treated with conformal external beam radiation therapy . Int J Radiat Oncol Biol Phys . 1998;41:1087–1092
  20. D’Amico AV , Whittington R , Malkowicz SB , et al.   Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer . JAMA . 1998;280:969–974
  21. Merrick GS , Butler WM , Wallner KE , et al.   Impact of supplemental external beam radiotherapy and/or androgen deprivation therapy on biochemical outcome after permanent prostate brachytherapy . Int J Radiat Oncol Biol Phys . 2005;61:32–43
  22. Padula GD , Zelefsky MJ , Venkatraman ES , et al.   Normalization of serum testosterone levels in patients treated with neoadjuvant hormonal therapy and three-dimensional conformal radiotherapy for prostate cancer . Int J Radiat Oncol Biol Phys . 2002;52:439–443
  23. Blasko JC , Grimm PD , Sylvester JE , et al.   Palladium-103 brachytherapy for prostate carcinoma . Int J Radiat Oncol Biol Phys . 2000;46:839–850
  24. Sharkey J , Cantor A , Solc Z , et al.   Brachytherapy versus radical prostatectomy in patients with clinically localized prostate cancer . Curr Urol Rep . 2002;3:250–257
  25. Brachman DG , Thomas T , Hilbe J , et al.   Failure-free survival following brachytherapy alone or external beam irradiation alone for T1-2 prostate tumors in 2222 patients: Results from a single practice . Int J Radiat Oncol Biol Phys . 2000;48:111–117
  26. Kollmeier MA , Stock RG , Stone N . Biochemical outcomes after prostate brachytherapy with 5-year minimal follow-up: Importance of patient selection and implant quality . Int J Radiat Oncol Biol Phys . 2003;57:645–653
  27. Kwok Y , DiBiase SJ , Amin PP , et al.   Risk group stratification in patients undergoing permanent (125)I prostate brachytherapy as monotherapy . Int J Radiat Oncol Biol Phys . 2002;53:588–594
  28. Stokes SH . Comparison of biochemical disease-free survival of patients with localized carcinoma of the prostate undergoing radical prostatectomy, transperineal ultrasound-guided radioactive seed implantation, or definitive external beam irradiation . Int J Radiat Oncol Biol Phys . 2000;47:129–136
  29. Zelefsky MJ , Hollister T , Raben A , et al.   Five-year biochemical outcome and toxicity with transperineal CT-planned permanent I-125 prostate implantation for patients with localized prostate cancer . Int J Radiat Oncol Biol Phys . 2000;47:1261–1266
  30. Ragde H , Korb LJ , Elgamal AA , et al.   Modern prostate brachytherapy (Prostate specific antigen results in 219 patients with up to 12 years of observed follow-up) . Cancer . 2000;89:135–141

 J.F.T.-R. is supported by a K08 CA108926-01 award from the NCI.

PII: S1078-1439(06)00007-X

doi: 10.1016/j.urolonc.2005.12.003

Urologic Oncology: Seminars and Original Investigations
Volume 24, Issue 5 , Pages 384-390 , September 2006