Urologic Oncology: Seminars and Original Investigations
Volume 24, Issue 6 , Pages 503-508 , November 2006

Treatment of a radiation-induced rectal ulcer with hyperbaric oxygen therapy in a man with prostate cancer

  • Mari Nakabayashi, M.D., Ph.D.

      Affiliations

    • Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA
    • Harvard Medical School, Boston, MA 02115, USA
    • ,
  • Clair Beard, M.D.

      Affiliations

    • Harvard Medical School, Boston, MA 02115, USA
    • Department of Radiation Oncology, Brigham and Women’s Hospital, Boston, MA 02115, USA
    • ,
  • Sandra M. Kelly, M.S., R.N., C.S., A.N.P.

      Affiliations

    • Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA
    • ,
  • David L. Carr-Locke, M.D.

      Affiliations

    • Harvard Medical School, Boston, MA 02115, USA
    • Division of Gastroenterology, Brigham and Women’s Hospital, Boston, MA 02115, USA
    • ,
  • William K. Oh, M.D.

      Affiliations

    • Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA
    • Harvard Medical School, Boston, MA 02115, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-617-632-4524; fax: +1-617-632-2165.

Received 6 September 2005 ,Revised 1 February 2006 ,Accepted 2 February 2006.

References 

  1. Cox JD, Stetz J, Pajak TF. Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC). Int J Radiat Oncol Biol Phys. 1995;31:1341–1346
  2. Cunningham IG. The management of radiation proctitis. Aust N Z J Surg. 1980;50:172–178
  3. Gilinsky NH, Burns DG, Barbezat GO, et al. The natural history of radiation-induced proctosigmoiditis: an analysis of 88 patients. Q J Med. 1983;52:40–53
  4. Perez CA, Michalski JM, Mansur D, et al. Three-dimensional conformal therapy versus standard radiation therapy in localized carcinoma of prostate: An update. Clin Prostate Cancer. 2002;1:97–104
  5. Teshima T, Hanks GE, Hanlon AL, et al. Rectal bleeding after conformal 3D treatment of prostate cancer: Time to occurrence, response to treatment and duration of morbidity. Int J Radiat Oncol Biol Phys. 1997;39:77–83
  6. Coia LR, Myerson RJ, Tepper JE. Late effects of radiation therapy on the gastrointestinal tract. Int J Radiat Oncol Biol Phys. 1995;31:1213–1236
  7. Pilepich MV, Asbell SO, Krall JM, et al. Correlation of radiotherapeutic parameters and treatment related morbidity–Analysis of RTOG Study 77–06. Int J Radiat Oncol Biol Phys. 1987;13:1007–1012
  8. Pilepich MV, Krall JM, Sause WT, et al. Correlation of radiotherapeutic parameters and treatment related morbidity in carcinoma of the prostate–Analysis of RTOG study 75–06. Int J Radiat Oncol Biol Phys. 1987;13:351–357
  9. Sanghani MV, Ching J, Schultz D, et al. Impact on rectal dose from the use of a prostate immobilization and rectal localization device for patients receiving dose escalated 3D conformal radiation therapy. Urol Oncol. 2004;22:165–168
  10. Pasquier D, Hoelscher T, Schmutz J, et al. Hyperbaric oxygen therapy in the treatment of radio-induced lesions in normal tissues: A literature review. Radiother Oncol. 2004;72:1–13
  11. Hovdenak N, Fajardo LF, Hauer-Jensen M. Acute radiation proctitis: A sequential clinicopathologic study during pelvic radiotherapy. Int J Radiat Oncol Biol Phys. 2000;48:1111–1117
  12. Boersma LJ, van den Brink M, Bruce AM, et al. Estimation of the incidence of late bladder and rectum complications after high-dose (70–78 GY) conformal radiotherapy for prostate cancer, using dose-volume histograms. Int J Radiat Oncol Biol Phys. 1998;41:83–92
  13. Kupelian PA, Reddy CA, Carlson TP, et al. Dose/volume relationship of late rectal bleeding after external beam radiotherapy for localized prostate cancer: absolute or relative rectal volume?. Cancer J. 2002;8:62–66
  14. Denham JW, O’Brien PC, Dunstan RH, et al. Is there more than one late radiation proctitis syndrome?. Radiother Oncol. 1999;51:43–53
  15. Brabbins D, Martinez A, Yan D, et al. A dose-escalation trial with the adaptive radiotherapy process as a delivery system in localized prostate cancer: Analysis of chronic toxicity. Int J Radiat Oncol Biol Phys. 2005;61:400–408
  16. Peeters ST, Heemsbergen WD, van Putten WL, et al. Acute and late complications after radiotherapy for prostate cancer: Results of a multicenter randomized trial comparing 68 Gy to 78 Gy. Int J Radiat Oncol Biol Phys. 2005;61:1019–1034
  17. Herold DM, Hanlon AL, Hanks GE. Diabetes mellitus: A predictor for late radiation morbidity. Int J Radiat Oncol Biol Phys. 1999;43:475–479
  18. Liu M, Pickles T, Agranovich A, et al. Impact of neoadjuvant androgen ablation and other factors on late toxicity after external beam prostate radiotherapy. Int J Radiat Oncol Biol Phys. 2004;58:59–67
  19. Tucker SL, Dong L, Cheung R, et al. Comparison of rectal dose-wall histogram versus dose-volume histogram for modeling the incidence of late rectal bleeding after radiotherapy. Int J Radiat Oncol Biol Phys. 2004;60:1589–1601
  20. Michalski JM, Winter K, Purdy JA, et al. Toxicity after three-dimensional radiotherapy for prostate cancer on RTOG 9406 dose Level V. Int J Radiat Oncol Biol Phys. 2005;62:706–713
  21. Baughan CA, Canney PA, Buchanan RB, et al. A randomized trial to assess the efficacy of 5-aminosalicylic acid for the prevention of radiation enteritis. Clin Oncol (R Coll Radiol). 1993;5:19–24
  22. Freund U, Scholmerich J, Siems H, et al. Unwanted side-effects in using mesalazine (5-aminosalicylic acid) during radiotherapy. [in German] Strahlenther Onkol. 1987;163:678–680
  23. Martenson JA, Hyland G, Moertel CG, et al. Olsalazine is contraindicated during pelvic radiation therapy: Results of a double-blind, randomized clinical trial. Int J Radiat Oncol Biol Phys. 1996;35:299–303
  24. Baum CA, Biddle WL, Miner PB. Failure of 5-aminosalicylic acid enemas to improve chronic radiation proctitis. Dig Dis Sci. 1989;34:758–760
  25. O’Brien PC, Franklin CI, Dear KB, et al. A phase III double-blind randomised study of rectal sucralfate suspension in the prevention of acute radiation proctitis. Radiother Oncol. 1997;45:117–123
  26. O’Brien PC, Franklin CI, Poulsen MG, et al. Acute symptoms, not rectally administered sucralfate, predict for late radiation proctitis: Longer term follow-up of a phase III trial–Trans-Tasman Radiation Oncology Group. Int J Radiat Oncol Biol Phys. 2002;54:442–449
  27. Martenson JA, Bollinger JW, Sloan JA, et al. Sucralfate in the prevention of treatment-induced diarrhea in patients receiving pelvic radiation therapy: A North Central Cancer Treatment Group phase III double-blind placebo-controlled trial. J Clin Oncol. 2000;18:1239–1245
  28. Chautems RC, Delgadillo X, Rubbia-Brandt L, et al. Formaldehyde application for haemorrhagic radiation-induced proctitis: A clinical and histological study. Colorectal Dis. 2003;5:24–28
  29. de Parades V, Etienney I, Bauer P, et al. Formalin application in the treatment of chronic radiation-induced hemorrhagic proctitis–An effective but not risk-free procedure: A prospective study of 33 patients. Dis Colon Rectum. 2005;48:1535–1541
  30. Cavcic J, Turcic J, Martinac P, et al. Metronidazole in the treatment of chronic radiation proctitis: Clinical trial. Croat Med J. 2000;41:314–318
  31. Kwon RS, Carr-Locke DL. Are we making progress with argon plasma coagulation in chronic radiation proctopathy?. J Gastroenterol Hepatol. 2005;20:171–172
  32. Venkatesh KS, Ramanujam P. Endoscopic therapy for radiation proctitis-induced hemorrhage in patients with prostatic carcinoma using argon plasma coagulator application. Surg Endosc. 2002;16:707–710
  33. Feldmeier JJ, Hampson NB. A systematic review of the literature reporting the application of hyperbaric oxygen prevention and treatment of delayed radiation injuries: An evidence based approach. Undersea Hyperb Med. 2002;29:4–30
  34. Woo TC, Joseph D, Oxer H. Hyperbaric oxygen treatment for radiation proctitis. Int J Radiat Oncol Biol Phys. 1997;38:619–622
  35. Warren DC, Feehan P, Slade JB, et al. Chronic radiation proctitis treated with hyperbaric oxygen. Undersea Hyperb Med. 1997;24:181–184
  36. Kitta T, Shinohara N, Shirato H, et al. The treatment of chronic radiation proctitis with hyperbaric oxygen in patients with prostate cancer. BJU Int. 2000;85:372–374
  37. Marx RE, Ehler WJ, Tayapongsak P, et al. Relationship of oxygen dose to angiogenesis induction in irradiated tissue. Am J Surg. 1990;160:519–524

PII: S1078-1439(06)00041-X

doi: 10.1016/j.urolonc.2006.02.002

Urologic Oncology: Seminars and Original Investigations
Volume 24, Issue 6 , Pages 503-508 , November 2006

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