Urologic Oncology: Seminars and Original Investigations
Volume 25, Issue 2 , Pages 120-127 , March 2007

Gene expression profile in squamous cell carcinoma of the urinary bladder using complementary deoxyribonucleic acid microarray

  • Ashraf A. Ewis, M.D., Ph.D.

      Affiliations

    • Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST-Shikoku), Takamatsu, Japan
    • Department of Public Health and Occupational Medicine, Faculty of Medicine, El-Minia University, El-Minia, Egypt
    • Corresponding Author InformationCorresponding author. Tel.: +81-87-869-4104; fax: +81-87-869-4113.
  • ,
  • Essam El-Samman, Ph.D.

      Affiliations

    • Department of Urology, The University of Tokushima School of Medicine, Tokushima, Japan
    • Department of Urology, Egyptian National Institute of Oncology, Sohag, Egypt
  • ,
  • Nermin Ali, M.D., Ph.D.

      Affiliations

    • Department of Pharmacology, The University of Tokushima School of Medicine, Tokushima, Japan
  • ,
  • Kazuaki Kajimoto, Ph.D.

      Affiliations

    • Division of Gene Expression, Institute for Genome Research, The University of Tokushima School of Medicine, Tokushima, Japan
  • ,
  • Yasuo Shinohara, Ph.D.

      Affiliations

    • Division of Gene Expression, Institute for Genome Research, The University of Tokushima School of Medicine, Tokushima, Japan
  • ,
  • Mitsuru Ishikawa, Ph.D.

      Affiliations

    • Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST-Shikoku), Takamatsu, Japan
  • ,
  • Hiro-Omi Kanayama, M.D., Ph.D.

      Affiliations

    • Department of Urology, The University of Tokushima School of Medicine, Tokushima, Japan
  • ,
  • Yoshinobu Baba, Ph.D.

      Affiliations

    • Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST-Shikoku), Takamatsu, Japan
    • Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Nagoya, Japan

Received 21 November 2005 ,Revised 20 March 2006 ,Accepted 21 March 2006.

References 

  1. Warren W, Biggs PJ, el-Baz M, et al. Mutations in the p53 gene in schistosomal bladder cancer: a study of 92 tumours from Egyptian patients and a comparison between mutational spectra from schistosomal and non-schistosomal urothelial tumours. Carcinogenesis. 1995;16:1181–1189
  2. Shokeir AA. Squamous cell carcinoma of the bladder: pathology, diagnosis and treatment. BJU Int. 2004;93:216–220
  3. Ghoneim MA, El-Mekresh MM, el-Baz MA, et al. Radical cystectomy for carcinoma of the bladder: Critical evaluation of the results in 1,026 cases. J Urol. 1997;158:393–399
  4. Ghoneim MA, Awaad HK. Results of treatment in carcinoma of the bilharzial bladder. J Urol. 1980;123:850–852
  5. Bahnson RR. Squamous cell carcinoma of the bladder. J Urol. 1997;157:2115
  6. Thykjaer T, Workman C, Kruhoffer M, et al. Identification of gene expression patterns in superficial and invasive human bladder cancer. Cancer Res. 2001;61:2492–2499
  7. Sanchez-Carbayo M, Socci ND, Charytonowicz E, et al. Molecular profiling of bladder cancer using cDNA microarrays: defining histogenesis and biological phenotypes. Cancer Res. 2002;62:6973–6980
  8. Sanchez-Carbayo M, Socci N, Lozano JJ, et al. Gene identification in bladder cancer progression using cDNA microarrays. Am J Pathol. 2003;163:505–516
  9. Dyrskjot L, Thykjaer T, Kruhoffer M, et al. Identifying distinct classes of bladder carcinoma using microarrays. Nat Genet. 2003;33:90–96
  10. Ramchurren N, Cooper K, Summerhayes IC. Molecular events underlying schistosomiasis-related bladder cancer. Int J Cancer. 1995;62:237–244
  11. Koyuncuoglu M, Kargi A, Cingoz S, et al. Investigation of p53, c-cerbB-2, PCNA immunoreactivity, DNA content, AgNOR and apoptosis in bladder carcinoma as prognostic parameters. Cancer Lett. 1998;126:143–148
  12. In:  Sobin LH,  Wittekind C editor. TNM classification of malignant tumors. 6thed.. New York (NY): Wiley-Liss; 2002;
  13. Golub TR, Slonim DK, Tamayo P, et al. Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring. Science. 1999;286:531–537
  14. Alizadeh AA, Eisen MB, Davis RE, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature. 2000;403:503–511
  15. Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature. 2000;406:747–752
  16. Bittner M, Meltzer P, Chen Y, et al. Molecular classification of cutaneous malignant melanoma by gene expression profiling. Nature. 2000;406:536–540
  17. Sorlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A. 2001;98:10869–10874
  18. van de Vijver MJ, He YD, van’t Veer LJ, et al. A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med. 2002;347:1999–2009
  19. van’t Veer LJ, Dai H, van de Vijver MJ, et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature. 2002;415:530–536
  20. Ramaswamy S, Ross KN, Lander ES, et al. A molecular signature of metastasis in primary solid tumors. Nat Genet. 2003;33:49–54
  21. Ami Y, Shimazui T, Akaza H, et al. Gene expression profiles correlate with the morphology and metastasis characteristics of renal cell carcinoma cells. Oncol Rep. 2005;13:75–80
  22. Dyrskjot L, Kruhoffer M, Thykjaer T, et al. Gene expression in the urinary bladder: A common carcinoma in situ gene expression signature exists disregarding histopathological classification. Cancer Res. 2004;64:4040–4048
  23. Orntoft TF, Thykjaer T, Waldman FM, et al. Genome-wide study of gene copy numbers, transcripts, and protein levels in pairs of non-invasive and invasive human transitional cell carcinomas. Mol Cell Proteomics. 2002;1:37–45
  24. Swellam M, Abd-Elmaksoud N, Halim MH, et al. Incidence of Bcl-2 expression in bladder cancer: Relation to schistosomiasis. Clin Biochem. 2004;37:798–802
  25. Badr KM, Nolen JD, Derose PB, et al. Muscle invasive schistosomal squamous cell carcinoma of the urinary bladder: Frequency and prognostic significance of p53, BCL-2, HER2/neu, and proliferation (MIB-1). Hum Pathol. 2004;35:184–189
  26. Liebert M, Washington R, Stein J, et al. Expression of the VLA beta 1 integrin family in bladder cancer. Am J Pathol. 1994;144:1016–1022
  27. Pfohler C, Fixemer T, Jung V, et al. In situ hybridization analysis of genes coding collagen IV alpha1 chain, laminin beta1 chain, and S-laminin in prostate tissue and prostate cancer: Increased basement membrane gene expression in high-grade and metastatic lesions. Prostate. 1998;36:143–150
  28. Stallmach A, von Lampe B, Matthes H, et al. Diminished expression of integrin adhesion molecules on human colonic epithelial cells during the benign to malignant tumor transformation. Gut. 1992;33:342–346
  29. Yasui W, Sano T, Nishimura K, et al. Expression of P-cadherin in gastric carcinomas and its reduction in tumor progression. Int J Cancer. 1993;54:49–52
  30. Sun W, Herrera GA. E-cadherin expression in urothelial carcinoma in situ, superficial papillary transitional cell carcinoma, and invasive transitional cell carcinoma. Hum Pathol. 2002;33:996–1000
  31. Sato H, Takino T, Okada Y, et al. A matrix metalloproteinase expressed on the surface of invasive tumor cells. Nature. 1994;370:61–65
  32. Suzuki E, Ota T, Tsukuda K, et al. nm23-H1 reduces in vitro cell migration and the liver metastatic potential of colon cancer cells by regulating myosin light chain phosphorylation. Int J Cancer. 2004;108:207–211
  33. Bertucci F, Salas S, Eysteries S, et al. Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters. Oncogene. 2004;23:1377–1391

PII: S1078-1439(06)00093-7

doi: 10.1016/j.urolonc.2006.03.006

Urologic Oncology: Seminars and Original Investigations
Volume 25, Issue 2 , Pages 120-127 , March 2007