Urologic Oncology: Seminars and Original Investigations
Volume 27, Issue 5 , Pages 466-472 , September 2009

Prostate-sparing cystectomy: A review of the oncologic and functional outcomes. Contraindicated in patients with bladder cancer

  • John P. Stein, M.D., FACS

      Affiliations

    • Department of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California 90089, USA
    • Deceased.
    • Corresponding Author InformationCorresponding author. Tel.: +1-323-865-3709; fax: +1-323-865-0120
  • ,
  • Richard E. Hautmann, M.D.

      Affiliations

    • The University of Ulm, Ulm, Germany
  • ,
  • David Penson, M.D.

      Affiliations

    • Department of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California 90089, USA
  • ,
  • Donald G. Skinner, M.D.

      Affiliations

    • Department of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California 90089, USA

Received 17 October 2007 ,Revised 18 December 2007 ,Accepted 31 December 2007.

References 

  1. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer J Clin. 2008;58:71–96
  2. Prout G, Marshall VF. The prognosis with untreated bladder tumors. Cancer. 1956;9:551–558
  3. Stein JP. Indications for early cystectomy. Urology. 2003;62:591–595
  4. Stein JP, Lieskovsky G, Cote R, et al. Radical cystectomy in the treatment of invasive bladder cancer: Long-term results in 1,054 patients. J Clin Oncol. 2001;19:666–675
  5. Ghoneim MA, El-Mekresh MM, El-Baz MA, et al. Radical cystectomy for carcinoma of the bladder: Critical evaluation of the results in 1,026 cases. J Urol. 1997;158:393–399
  6. Montie JE. Against bladder sparing surgery. J Urol. 1999;162:452–455
  7. Stein JP, Skinner DG. Orthotopic bladder replacement. In:  Walsh PC,  Retik AB,  Vaughan ED, et al. editor. Campbell's Urology. 8th ed.. Philadelphia, PA: W. B. Saunders; 2002;p. 3835–3864
  8. Spitz A, Stein JP, Lieskovsky G, et al. Orthotopic urinary diversion with preservation of erectile and ejaculatory function in men requiring radical cystectomy for nonurothelial malignancy: A new technique. J Urol. 1999;161:1761–1764
  9. Muto G, Bardari F, D'urso L, et al. Seminal sparing cystectomy and ileocapsuloplasty: Long-term follow-up results. J Urol. 2004;172:76–80
  10. Vallancien G, El Fettouh HA, Cathelineau X, et al. Cystectomy with prostate sparing for bladder cancer in 100 patients: 10-year experience. J Urol. 2002;168:2413–2417
  11. Colombo R, Bertini R, Salonia A, et al. Nerve and seminal sparing radical cystectomy with orthotopic urinary diversion for selected patients with superficial bladder cancer: An innovative surgical approach. J Urol. 2001;165:51–55
  12. Terrone C, Cracco C, Scarpa RM, et al. Supra-ampullary cystectomy with preservation of sexual function and ileal orthotopic reservoir for bladder tumor: Twenty years of experience. Eur Urol. 2004;46:264–270
  13. Meinhardt W, Horenblas S. Sexuality-preserving cystectomy and neobladder (SPCN): Functional results of a neobladder anastomosed to the prostate. Eur Urol. 2003;43:646–650
  14. Ghanem AN. Experience with “capsule sparing” cystoprostatectomy for orthotopic bladder replacement: Overcoming the problems of impotence, incontinence, and difficult urethral anastomosis. B J U Int. 2002;90:617–620
  15. Nieuwenhuijzen JA, Meinhardt W, Horenblas S. Clincal outcomes after sexuality preserving cystectomy and neobladder (prostate sparing cystectomy) in four patients. J Urol. 2005;173:1314–1317
  16. Botto H, Sebe P, Molinie V, et al. Prostatic capsule- and seminal-sparing cystectomy for bladder cancer: Initial results for selected patients. BJU Int. 2004;94:1021–1025
  17. Martis G, D'Eia G, Diana M, et al. Prostatic capsule- and nerve-sparing cystectomy in organ-confined bladder cancer: Preliminary results. World J Surg. 2005;10:1277–1281
  18. Arroyo C, Andrees H, Rozet F, et al. Laparoscopic prostate-sparing radical cystectomy: The Montsouris technique and preliminary results. J Endourol. 2005;13:424–428
  19. Saidi A, Nahon O, Daniel L, et al. Prostate-sparing cystectomy: Long-term functional and oncological results in a series of 25 cases. Prog Urol. 2004;14:172–177
  20. Horenblas S, Meinhardt W, Ijzerman W, et al. Sexuality preserving cystectomy and neobladder: Initial results. J Urol. 2001;166:837–840
  21. Colombo R, Bertini R, Salonia A, et al. Overall clinical outcomes after nerve and seminal sparing radical cystectomy for the treatment of organ confined bladder cancer. J Urol. 2004;171:1819–1822
  22. Sebe P, Traxer O, Cussenot O, et al. Cystectomy with preservation of the prostate in the treatment of bladder tumors: Anatomical basis, surgical techniques, indications and results. Prog Urol. 2003;13:1279–1285
  23. Scardino PT, Weaver R, Hudson MA. Early detection of prostate cancer. Hum Pathol. 1992;23:211
  24. Revelo MP, Cookson MS, Chang SS, et al. Incidence and location of prostate and urothelial carcinoma in prostates from cystoprostatectomies: Implications in prostates for possible apical sparing surgery. J Urol. 2004;171:646–651
  25. Winfield HN, Reddy PK, Lange PH. Coexisting adenocarcinoma of the prostate in patients undergoing cystoprostatectomy for bladder cancer. Urology. 1987;30:100–101
  26. Kabalin JN, McNeal JE, Price HM, et al. Unsuspected adenocarcinoma of the prostate in patients undergoing cystoprostatectomy for other causes: Incidence, histology, and morphometric observations. J Urol. 1989;141:1091–1094
  27. Montie JE, Wood DP, Pontes JE, et al. Adenocarcinoma of the prostate in cystoprostatectomy specimens removed for bladder cancer. Cancer. 1989;63:381–385
  28. Abbas F, Hochberg D, Givantos F, et al. Incidental prostatic adenocarcinoma in patients undergoing radical cystoprostatectomy for bladder cancer. Eur Urol. 1996;30:322–326
  29. Plante P, Lesourd A, Blanchet P, et al. Can the prostatic capsule be preserved during cystectomy for bladder tumors: A study of urethra and prostatic involvement in the cystectomy specimen. Prog Urol. 1998;8:47–50
  30. Moutzouris G, Barbatis C, Plastiras D, et al. Incidence and histological findings of unsuspected prostatic adenocarcinoma in radical cystoprostatectomy for transitional cell carcinoma of the bladder. Scand J Urol Nephrol. 1999;33:27–30
  31. Hautmann SH, Conrad S, Henke RP, et al. Detection rate of histologically insignificant prostate cancer with systematic sextant biopsies and fine needle aspiration cytology. J Urol. 2000;163:1734–1738
  32. Reese JR, Freiha FS, Gelb AB, et al. Transition cell carcinoma of the prostate in patients undergoing radical cystoprostatectomy. J Urol. 1992;147:92–95
  33. Wood DP, Montie JE, Pontes JE, et al. Transitional cell carcinoma of the prostate in cystoprostatectomy specimens removed for bladder cancer. J Urol. 1989;141:346–349
  34. Stein JP, Clark P, Miranda G, et al. Urethral tumor recurrence following cystectomy and urinary diversion: Clinical and pathological characteristics in 768 male patients. J Urol. 2005;173:1163–1168
  35. Iselin CE, Robertson CN, Webster GD, et al. Does prostate transitional cell carcinoma preclude orthotopic bladder reconstruction after cystoprostatectomy for bladder cancer?. J Urol. 1997;158:2123–2126
  36. Ngninkeu BN, Lorge F, Moulin P, et al. Transitional cell carcinoma involving the prostate: A clinicopathological retrospective study of 76 cases. J Urol. 2003;169:149–152
  37. Esrig D, Freeman JA, Elmajian DA, et al. Transitional cell carcinoma involving the prostate with a proposed staging classification for stroma invasion. J Urol. 1996;156:1071–1076
  38. Steers WD. Orthotopic neobladder: Functional outcomes. World J Urol. 2000;18:330–337
  39. Kessler TM, Burkhard FC, Studer UE. Clinical indications and outcomes with nerve-sparing cystectomy in patients with bladder cancer. Urol Clin N Am. 2005;32:165–175
  40. Madersbacher S, Mohrle K, Burkhard F, et al. Long-term voiding pattern of patients with ileal orthotopic bladder substitutes. J Urol. 2002;167:2052
  41. Koraitim MM, Atta MA, Foda MK. Impact of the prostatic apex on continence and urinary flow in patients with intestinal neobladders. Brit J Urol. 1996;78:534–536
  42. Hautmann RE, Stein JP. Neobladder with prostatic capsule and seminal-sparing cystectomy for bladder cancer: A step in the wrong direction. Urol Clin N Am. 2005;32:177–185
  43. Ward JF, Bartsch G, Sebo TJ, et al. Pathologic characterization of prostate cancers with a very low serum prostate specific antigen (0–2 ng/dl) incidental to cystoprostatectomy: Is PSA a useful indicator of clinical significance?. Urol Oncol. 2004;22:40–47

PII: S1078-1439(08)00007-0

doi: 10.1016/j.urolonc.2007.12.014

Urologic Oncology: Seminars and Original Investigations
Volume 27, Issue 5 , Pages 466-472 , September 2009