Urologic Oncology: Seminars and Original Investigations
Volume 28, Issue 4 , Pages 355-359 , July 2010

Kinetics of serum total and free prostate-specific antigen (PSA) after extended multisite prostate biopsy: Comparison among biopsy, transurethral resection of the prostate (TURP), and biopsy plus TURP

  • Noboru Hara, M.D., Ph.D.

      Affiliations

    • Division of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81-25-227-2287; fax: +81-25-227-0784
    • ,
  • Hiroshi Koike, M.D.

      Affiliations

    • Department of Urology, Niigata Rousai Hospital, Niigata, Japan
    • ,
  • Tomohiro Nobushita, M.D.

      Affiliations

    • Department of Urology, Niigata Rousai Hospital, Niigata, Japan
    • ,
  • Norio Miyajima, M.D.

      Affiliations

    • Department of Urology, Niigata Rousai Hospital, Niigata, Japan
    • ,
  • Makoto Kawaguchi, M.D., Ph.D.

      Affiliations

    • Department of Pathology, Niigata Rousai Hospital, Niigata, Japan
    • ,
  • Tsutomu Nishiyama, M.D., Ph.D.

      Affiliations

    • Division of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
    • ,
  • Kota Takahashi, M.D., Ph.D.

      Affiliations

    • Division of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
    • ,
  • Rudolf Hohenfellner, M.D., Ph.D.

      Affiliations

    • Department of Urology, Johannes Gutenberg University, Mainz, Germany

Received 16 July 2008 ,Revised 10 October 2008 ,Accepted 10 October 2008.

References 

  1. Partin AW, Catalona WJ, Southwick PC, et al. Analysis of percent free prostate-specific antigen (PSA) for prostate cancer detection: Influence of total PSA, prostate volume, and age. Urology. 1996;48:55–61
  2. Bangma CH, Kranse R, Blijenberg BG, et al. The value of screening tests in the detection of prostate cancer (Part II. Retrospective analysis of free/total prostate-specific analysis ratio, age-specific reference ranges, and PSA density). Urology. 1995;46:779–784
  3. Hara N, Kitamura Y, Saito T, et al. Total and free prostate-specific antigen indexes in prostate cancer screening: Value and limitation for Japanese populations. Asian J Androl. 2006;8:429–434
  4. Sotelo RJ, Mora KE, Pérez LH, et al. Assay standardization bias: Different prostate cancer detection rates and clinical outcomes resulting from different assays for free and total prostate-specific antigen. Urology. 2007;69:1143–1146
  5. Zhang WM, Leinonen J, Kalkkinen N, et al. Prostate-specific antigen forms a complex with and cleaves alpha 1-protease inhibitor in vitro. Prostate. 1997;33:87–96
  6. Recker F, Kwiatkowski MK, Pettersson K, et al. Enhanced expression of prostate-specific antigen in the transition zone of the prostate (A characterization following prostatectomy for benign hyperplasia). Eur Urol. 1998;33:549–555
  7. Catalona WJ, Smith DS, Wolfert RL, et al. Evaluation of percentage of free serum prostate-specific antigen to improve specificity of prostate cancer screening. JAMA. 1995;274:1214–1220
  8. Hodge KK, McNeal JE, Terris MK, et al. Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate. J Urol. 1989;142:71–75
  9. Fink KG, Hutarew G, Pytel A, et al. One 10-core prostate biopsy is superior to two sets of sextant prostate biopsies. BJU Int. 2003;92:385–388
  10. Mian BM, Naya Y, Okihara K, et al. Predictors of cancer in repeat extended multisite prostate biopsy in men with previous negative extended multisite biopsy. Urology. 2002;60:836–840
  11. Fink KG, Hutarew G, Lumper W, et al. Prostate cancer detection with two sets of 10-core compared with two sets of sextant biopsies. Urology. 2001;58:735–739
  12. Furuno T, Demura T, Kaneta T, et al. Difference of cancer core distribution between first and repeat biopsy: In patients diagnosed by extensive transperineal ultrasound guided template prostate biopsy. Prostate. 2004;58:76–81
  13. Kawata N, Miller GJ, Crawford ED, et al. Laterally directed biopsies detect more clinically threatening prostate cancer: Computer simulated results. Prostate. 2003;57:118–128
  14. Hara N, Okuizumi M, Koike H, et al. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a useful modality for the precise detection and staging of early prostate cancer. Prostate. 2005;62:140–147
  15. Cetinkaya M, Ulusoy E, Aki T, et al. Effect of transurethral resection on serum free/total prostate-specific antigen levels in patients with benign prostatic hyperplasia. Urology. 1999;53:118–120
  16. Oesterling JE, Rice DC, Glenski WJ, et al. Effect of cystoscopy, prostate biopsy, and transurethral resection of prostate on serum prostate-specific antigen concentration. Urology. 1993;42:276–282
  17. Hara N, Koike H, Ogino S, et al. Application of serum PSA to identify acute bacterial prostatitis in patients with fever of unknown origin or symptoms of acute pyelonephritis. Prostate. 2004;60:282–288
  18. Hara N, Kasahara T, Kawasaki T, et al. Frequency of PSA-mRNA-bearing cells in the peripheral blood of patients after prostate biopsy. Br J Cancer. 2001;85:557–562
  19. Ornstein DK, Rao GS, Smith DS, et al. Effect of digital rectal examination and needle biopsy on serum total and percentage of free prostate specific antigen levels. J Urol. 1997;157:195–198

PII: S1078-1439(08)00281-0

doi: 10.1016/j.urolonc.2008.10.014

Urologic Oncology: Seminars and Original Investigations
Volume 28, Issue 4 , Pages 355-359 , July 2010

Article Tools

* Image Usage & Resolution