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Urologic Oncology: Seminars and Original Investigations
Volume 27, Issue 6
, Pages 585-591
, November 2009
Friend or foe? Role of peroxisome proliferator-activated receptor-γ in human bladder cancer
References
- Cancer statistics, 2007. CA: Cancer J Clin. 2007;57:43–66
- Phase III trial of methotrexate, vinblastine, doxorubicin, and cisplatin versus carboplatin and paclitaxel in patients with advanced carcinoma of the urothelium. Cancer. 2004;100:1639–1645
- Seven year update of an EORTC phase III trial of high-dose intensity M-VAC chemotherapy and G-CSF versus classic M-VAC in advanced urothelial tract tumours. Eur J Cancer. 2006;42:50–54
- COX and PPAR: Possible interactions in pancreatic cancer. Pancreas. 2004;29:247–253
- EP1-4 subtype, COX, and PPAR γ receptor expression in colorectal cancer in prediction of disease-specific mortality. Int Journal Cancer. 2007;121:232–240
- Parvin-beta inhibits breast cancer tumorigenicity and promotes CDK9-mediated peroxisome proliferator-activated receptor γ 1 phosphorylation. Mol Cell Biol. 2008;28:687–704
- Peroxisome proliferator-activated receptor (PPAR) γ gene polymorphisms and colorectal cancer risk among Chinese in Singapore. Carcinogenesis. 2006;27:1797–1802
- . The expression of PPAR γ in gastric cancer. Nippon Rinsho. 2001;59(Suppl 4):595–597
- PPAR γ ligand-induced apoptosis through a p53-dependent mechanism in human gastric cancer cells. Cancer science. 2003;94:338–343
- . The PPAR-γ agonist pioglitazone post-transcriptionally induces p21 in PC3 prostate cancer but not in other cell lines. Cell cycle (Georgetown). 2005;4:582–584
- MAZ drives tumor-specific expression of PPAR γ 1 in breast cancer cells. Breast Cancer Res Treat. 2008;111:103–111
- . Peroxisome proliferator-activated receptors (PPARs): Nuclear receptors at the crossroads between lipid metabolism and inflammation. Inflamm Res. 2000;49:497–505
- Dietary fat, genes, and human health. Advances in experimental medicine and biology. 1997;422:167–176
- Mechanisms leading to COX-2 expression and COX-2 induced tumorigenesis: Topical therapeutic strategies targeting COX-2 expression and activity. Anticancer Agents Med Chem. 2006;6:187–208
- . Antineoplastic effects of peroxisome proliferator-activated receptor γ agonists. Lancet Oncol. 2004;5:419–429
- . PPAR trilogy from metabolism to cancer. Curr Opin Clin Nutr Metabolic Care. 2004;7:397–402
- PPARγ as a therapeutic target for tumor angiogenesis and metastasis. Cancer Biol Ther. 2005;4:687–693
- The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR). Toxicol Sci. 2006;90:269–295
- Can PPARγ ligands be used in cancer therapy?. Cur Med Chem. 2004;4:465–477
- . Central role of peroxisome proliferator-activated receptors in the actions of peroxisome proliferators. Annu Rev Pharmacol Toxicol. 2000;40:491–518
- Differential activation of adipogenesis by multiple PPAR isoforms. Genes Dev. 1996;10:974–984
- Effects of PPAR and RXR ligands in semaphorin 6B gene expression of human MCF-7 breast cancer cells. Int J Oncol. 2006;28:977–984
- . PPARγ induces cell cycle withdrawal: Inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A. Genes Dev. 1997;11:1987–1998
- . Studies of synergistic and antagonistic combinations of conventional cytotoxic agents with the multiple eicosanoid pathway modulator LY 293111. Anticancer Drugs. 2004;15:877–881
- A new class of peroxisome proliferator-activated receptor γ (PPARγ) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3′-indolyl)-1-(p-substituted phenyl)methanes. Mol Cancer Ther. 2004;3:247–260
- Expression of peroxisome proliferator-activated receptor (PPAR)γ in gastric cancer and inhibitory effects of PPARγ agonists. Br J Cancer. 2000;83:1394–1400
- Expression of peroxisome proliferator-activated receptors (PPARs) in human urinary bladder carcinoma and growth inhibition by its agonists. Int J Cancer. 2003;104:597–602
- Expression of peroxisome proliferator-activated receptor (PPAR) in human prostate cancer. The Prostate. 2002;51:108–116
- PPARγ-regulated tight junction development during human urothelial cytodifferentiation. J Cell Physiol. 2006;208:407–417
- The role of peroxisome proliferator-activated receptor γ in bladder cancer in relation to angiogenesis and progression. Gen Pharmacol. 2000;35:269–275
- Role of peroxisome proliferator-activated receptor γ and its ligands in non-neoplastic and neoplastic human urothelial cells. Am J Pathol. 2001;159:591–597
- Expression of peroxisome proliferator-activated receptor γ (PPARγ) in human transitional bladder cancer and its role in inducing cell death. Neoplasia (New York). 1999;1:330–339
- PAX8-PPARγ1 fusion oncogene in human thyroid carcinoma [corrected]. Science (New York). 2000;289:1357–1360
- Loss-of-function mutations in PPAR γ associated with human colon cancer. Mol Cell. 1999;3:799–804
- Inhibition of rat mammary gland carcinogenesis by simultaneous targeting of cyclooxygenase-2 and peroxisome proliferator-activated receptor γ. Cancer Res. 2004;64:1181–1189
- A new ligand for the peroxisome proliferator-activated receptor-γ (PPAR-γ), GW7845, inhibits rat mammary carcinogenesis. Cancer Res. 1999;59:5671–5673
- Ligands for peroxisome proliferator-activated receptors alpha and γ inhibit chemically induced colitis and formation of aberrant crypt foci in rats. Cancer Res. 2001;61:2424–2428
- Troglitazone, a ligand for peroxisome proliferator-activated receptor γ, inhibits chemically-induced aberrant crypt foci in rats. Jpn J Cancer Res. 2001;92:396–403
- Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in C57BL/6J-APCMin/+ mice. Nat Med. 1998;4:1053–1057
- Activators of the nuclear receptor PPARγ enhance colon polyp formation. Nat Medicine. 1998;4:1058–1061
- Loss of the peroxisome proliferation-activated receptor γ (PPARγ) does not affect mammary development and propensity for tumor formation but leads to reduced fertility. J Biol Chem. 2002;277:17830–17835
- 15-Deoxy-δ12,14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle cells. J Biol Chem. 2001;276:48950–48955
- . Activation of peroxisome proliferator-activated receptor-107 inhibits apoptosis induced by serum deprivation in LLC-PK1 cells. Exp Nephrol. 2002;10:393–401
- Thiazolidinedione activation of peroxisome proliferator-activated receptor γ can enhance mitochondrial potential and promote cell survival. J Biol Chemistry. 2002;277:31781–31788
- Polymorphisms in inflammation genes and bladder cancer: From initiation to recurrence, progression, and survival. J Clin Oncol. 2005;23:5746–5756
- Inhibition of bladder tumor growth by 1,1-bis(3>29>-indolyl)-1-(p-substituted phenyl) methanes: A new class of peroxisome proliferator-activated receptor γ agonists. Cancer Res. 2006;66:412–418
- Differential regulation of vascular endothelial growth factor expression by peroxisome proliferator-activated receptors in bladder cancer cells. J Biol Chem. 2002;277:23534–23543
- Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J Biol Chem. 1995;270:19761–19766
- Vascular endothelial growth factor is a predictor of relapse and stage progression in superficial bladder cancer. Cancer Res. 1997;57:5281–5285
- What is the optimal regimen for BCG intravesical therapy? (Are six weekly instillations necessary?). Eur Urol. 2000;37:470–477
- . A combination of intravesical BCG [corrected] and [corrected] electromotive mitomycin for high-risk superficial bladder cancer. Nat Clin Pract. 2006;3:472–473
- Bladder cancer clinical guidelines panel summary report on the management of nonmuscle invasive bladder cancer (stages Ta, T1, and TIS). Am Urol Assoc, J Urol. 1999;162:1697–1701
- Guidelines on bladder cancer. Eur Urol. 2002;41:105–112
- . Intravesical bacillus Calmette-Guerin reduces the risk of progression in patients with superficial bladder cancer: A meta-analysis of the published results of randomized clinical trials. J Urol. 2002;168:1964–1970
- Bacillus Calmette-Guerin induces the expression of peroxisome proliferator-activated receptor γ in bladder cancer cells. Int J Mol Med. 2006;17:269–273
- NKT cell defects in NOD mice suggest therapeutic opportunities. J Autoimmune. 2002;19:117–128
- Only multiple autoantibodies to islet cells (ICA), insulin, GAD65, IA-2, and IA-2β predict immune-mediated (type 1) diabetes in relatives. J Autoimmune. 1999;12:279–287
- The nuclear eicosanoid receptor, PPARγ, is aberrantly expressed in colonic cancers. Carcinogenesis. 1998;19:49–53
- Target genes of peroxisome proliferator-activated receptor γ in colorectal cancer cells. J Biol Chem. 2001;276:29681–29687
- An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ). J Biol Chem. 1995;270:12953–12956
- Therapeutic potential of thiazolidinediones as anticancer agents. Expert Opin Investig Drugs. 2003;12:1925–1937
- Somatic cell hybrid analyses of hematopoietic differentiation. Blood. 1981;58:1159–1163
- . Peroxisome-proliferator-activated receptors and cancers: Complex stories. Nat Rev. 2004;4:61–70
- . Peroxisome proliferator activated receptor-γ ligands as potent antineoplastic agents. Curr Med Chem. 2003;3:239–251
- Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor γ and the retinoid X receptor. Proc Natl Acad Sci USA. 1997;94:237–241
- . Activation of PPARγ leads to inhibition of anchorage-independent growth of human colorectal cancer cells. Gastroenterology. 1998;115:1049–1055
- Ligands for peroxisome proliferator-activated receptor γ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc Natl Acad Sci USA. 1998;95:8806–8811
- Ligand for peroxisome proliferator-activated receptor γ (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo. Cancer Res. 1998;58:3344–3352
- Differentiation and reversal of malignant changes in colon cancer through PPARγ. Nat Med. 1998;4:1046–1052
- . Activation of mitogen-activated protein kinases by peroxisome proliferator-activated receptor ligands: An example of nongenomic signaling. Mol Pharmacol. 2005;68:933–941
- . PPARγ signaling: One size fits all?. Cell Cycle (Georgetown). 2004;3:1352–1354
- Safety issues and prospects for future generations of PPAR modulators. Biochim Biophys Acta. 2007;1771:1065–1081
PII: S1078-1439(08)00327-X
doi: 10.1016/j.urolonc.2008.11.002
© 2009 Elsevier Inc. All rights reserved.
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Urologic Oncology: Seminars and Original Investigations
Volume 27, Issue 6
, Pages 585-591
, November 2009
