« Previous
Next »
Urologic Oncology: Seminars and Original Investigations
Volume 28, Issue 2
, Pages 189-194
, March 2010
Prevention of urinary bladder cancer in the FHIT knock-out mouse with Rofecoxib, a Cox-2 inhibitor
References
- Chemopreventive drug development: perspectives and progress. Cancer Epidemiol Biomarkers Prev. 1994;3:85–98
- . Nonsteroidal anti-inflammatory drugs for the prevention and treatment of cancer. J Intern Med. 2005;258:115–123
- Cyclooxygenase in biology and disease. FASEB J. 1998;12:1063–1073
- . Early trials probe COX-2 inhibitors' cancer-fighting potential. J Natl Cancer Inst. 1999;91:1186–1187
- COX-3 a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression. PNAS. 2002;99:13926–13931
- Mechanisms and applications of non-steroidal anti-inflammatory drugs in the chemoprevention of cancer. Mutat Res. 2003;523/4:137–144
- Rofecoxib [Vioxx, MK-0966; 4-(4′-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: A potent and orally active cyclooxygenase-2 inhibitor pharmacological and biochemical profiles. J Pharmacol Exp Ther. 1999;290:551–560
- . Cyclooxygenase-2 inhibitors: A new class of anti-inflammatory agents that spare the gastrointestinal tract. Gastroenterol Clin North Am. 1996;25:363–372
- COX-2 is expressed in human pulmonary, colonic, and mammary tumors. Cancer. 2000;89:2637–2645
- Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis. Mol Carcinog. 1999;25:231–240
- Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer. Cancer Res. 1999;59:987–990
- Expression of cyclooxygenase-2 in human gastric carcinoma. Cancer Res. 1997;57:1276–1280
- Rationale for use of cyclooxygenase-2 inhibitors in prevention and treatment of bladder cancer. Urology. 2004;64:637–642
- Relation between cyclooxygenase-2 expression and clinicopathologic parameters with patient prognosis in transitional cell carcinoma of the bladder. Urol Int. 2006;76:51–56
- . Cyclooxygenase-2 expression is up-regulated in transitional cell carcinoma and its preneoplastic lesions in the human urinary bladder. Clin Cancer Res. 2000;6:2424–2430
- Cyclooxygenase-2 expression increases with the stage and grade in transitional cell carcinoma of the urinary bladder. Int Urol Nephrol. 2005;37:47–53
- . Association of cyclooxygenase-2 expression with prognosis of stage T1 grade 3 bladder cancer. Urology. 2002;60:816–821
- Increased expression of cyclooxygenase-2 protein in rat urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl) nitrosamine. Carcinogenesis. 1999;20:2305–2310
- Chemopreventive effects of cyclooxygenase-2 inhibitor and epidermal growth factor-receptor kinase inhibitor on rat urinary bladder carcinogenesis. BJU Int. 2006;97:640–643
- Celecoxib inhibits N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder cancers in male B6D2F1 mice and female Fischer-344 rats. Cancer Res. 2000;60:5599–5602
- Chemopreventive effects of nimesulide, a selective cyclooxygenase-2 inhibitor, on the development of rat urinary bladder carcinomas initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine. Cancer Res. 1998;58:3028–3031
- 4-Hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers in mice: Characterization of FHIT and survivin expression and chemopreventive effects of indomethacin. Carcinogenesis. 2005;26:571–578
- Inactivation of the FHIT gene favors bladder cancer development. Clin Cancer Res. 2004;10:7607–7612
- The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell. 1996;84:587–597
- Loss of FHIT expression in transitional cell carcinoma of the urinary bladder. Am J Pathol. 2000;156:419–424
- Cancer statistics, 2007. CA Cancer J Clin. 2007;57:43–66
- Molecular genetics of bladder cancer: Targets for diagnosis and therapy. J Exp Clin Cancer Res. 2006;25:145–160
- Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. NEJM. 2000;343:1520–1528
- Fragile genes as biomarkers: Epigenetic control of WWOX and FHIT in lung, breast and bladder cancer. Oncogene. 2005;24:1625–1633
- Expression of cyclooxygenase-2 in human transitional cell carcinoma of the urinary bladder. Am J Pathol. 2001;158:849–853
- The relationship between the systemic inflammatory response, tumor proliferative activity, T-lymphocytic infiltration and COX-2 expression and survival in patients with transitional cell carcinoma of the urinary bladder. Br J Cancer. 2006;95:1234–1238
- FHIT gene expression in human urinary bladder transitional cell carcinomas. In Vivo. 2001;15:169–173
- CpG island methylation in Schistosoma- and non-Schistosoma-associated bladder cancer. Mod Pathol. 2004;17:1268–1274
- FHIT gene therapy prevents tumor development in FHIT-deficient mice. Proc Natl Acad Sci USA. 2001;98:3346–3351
- Muir-Torre-like syndrome in FHIT-deficient mice. Proc Natl Acad Sci USA. 2000;97:4742–4747
☆ This work was supported by a Merck and Co., Inc. Medical School grant.
PII: S1078-1439(09)00008-8
doi: 10.1016/j.urolonc.2009.01.016
© 2010 Elsevier Inc. All rights reserved.
« Previous
Next »
Urologic Oncology: Seminars and Original Investigations
Volume 28, Issue 2
, Pages 189-194
, March 2010
