Urologic Oncology: Seminars and Original Investigations
Volume 28, Issue 3 , Pages 251-259 , May 2010

Ablative therapies in the treatment of small renal tumors: How far from standard of care?

  • Paolo Gontero, M.D.

      Affiliations

    • Department of Urology, University of Studies of Torino, Torino, Italy
    • Corresponding Author InformationCorresponding author. Tel.: +390116335581; fax: +390116334202.
    • ,
  • Steven Joniau, M.D.

      Affiliations

    • Department of Urology, University of Leuven, Leuven, Belgium
    • ,
  • Andrea Zitella, M.D.

      Affiliations

    • Department of Urology, University of Studies of Torino, Torino, Italy
    • ,
  • Thomas Tailly, M.D.

      Affiliations

    • Department of Urology, University of Leuven, Leuven, Belgium
    • ,
  • Alessandro Tizzani, M.D.

      Affiliations

    • Department of Urology, University of Studies of Torino, Torino, Italy
    • ,
  • Hein Van Poppel, M.D.

      Affiliations

    • Department of Urology, University of Leuven, Leuven, Belgium
    • ,
  • Ziya Kirkali, M.D.

      Affiliations

    • Dokuz Eylul University, School of Medicine, Izmir, Turkey

Received 3 March 2009 ,Revised 8 June 2009 ,Accepted 11 June 2009.

References 

  1. Perrotti M, Badger WJ, McLeod D, et al. Does laparoscopy beget underuse of partial nephrectomy for T(1) renal masses? (Competing treatment decision pathways may influence utilization). J Endourol. 2007;21:1223–1228
  2. Phillips B, Ball C, Sackett D, et al. Levels of evidence and grades of recommendation (Oxford Centre for Evidence based Medicine). http://www.cebm.net/levels_of_evidence.asp
  3. Acker JP, Larese A, Yang H, et al. Intracellular ice formation is affected by cell interactions. Cryobiology. 1999;38:363–371
  4. Hoffmann NE, Bischof JC. The cryobiology of cryosurgical injury. Urology. 2002;60(Suppl 1):40–49
  5. Baust JG, Gage AA. The molecular basis of cryosurgery. BJU Int. 2005;95:1187–1191
  6. Mouraviev V, Joniau S, Van Poppel H, et al. Current status of minimally invasive ablative techniques in the treatment of small renal tumors. Eur Urol. 2007;51(2):328–336
  7. Woolley ML, Schulsinger DA, Durand DB, et al. Effect of freezing parameters (freeze cycle and thaw process) on tissue destruction following renal cryoablation. J Endourol. 2002;16:519–522
  8. Cestari A, Guazzoni G, Buffi NM, et al. Laparoscopic cryoablation of small renal masses: Technique and results after 6-year experience. Eur Urol Suppl. 2007;6:646–652
  9. Gill IS, Remer EM, Hasan WA, et al. Renal cryoablation: Outcome at 3 years. J Urol. 2005;173:1903–1907
  10. Chosy SG, Nakada SY, Lee FT, et al. Monitoring renal cryosurgery: Predictors of tissue necrosis in swine. J Urol. 1998;159:1370–1374
  11. Campbell SC, Krishnamurthi V, Chow G, et al. Renal cryosurgery: Experimental evaluation of treatment parameters. Urology. 1998;52:29–33
  12. Permpongkosol S, Nielsen ME, Solomon SB. Percutaneous renal cryoablation. Urology. 2006;68(1 Suppl):19–25
  13. Deane LA, Clayman RV. Review of minimally invasive renal therapies: Needle-based and extracorporeal. Urology. 2006;68(1 Suppl):26–37
  14. Schwartz BF, Rewcastle JC, Powell T, et al. Cryoablation of small peripheral renal masses: A retrospective analysis. Urology. 2006;68(1 Suppl):14–18
  15. Stein RJ, Kaouk JH. Renal cryotherapy: A detailed review including a 5-year follow-up. BJU Int. 2007;99(5 Pt B):1265–1270
  16. Wyler SF, Sulser T, Ruszat R, et al. Intermediate-term results of retroperitoneoscopy-assisted cryotherapy for small renal tumors using multiple ultrathin cryoprobes. Eur Urol. 2007;51:971–979
  17. Silverman SG, Tuncali K, vanSonnenberg E, et al. Renal tumors: MR imaging-guided percutaneous cryotherapy—initial experience in 23 patients. Radiology. 2005;236:716–724
  18. Gupta A, Allaf ME, Kavoussi LR, et al. Computerized tomography guided percutaneous renal cryoablation with the patient under conscious sedation: Initial clinical experience. J Urol. 2006;175:447–452
  19. Shingleton WB, Sewell PE. Cryoablation of renal tumors in patients with solitary kidneys. BJU Int. 2003;92:237–239
  20. Milner J, Borge M, Sharma S, et al. Percutaneous CT guided saline mobilization of colon to facilitate renal cryoablation of small renal tumors. J Urol. 2005;173(Suppl):320;[Abstract 1181].
  21. Shingleton WB, Sewell PE. Percutaneous renal cryoablation of renal tumors in patients with von Hippel-Lindau disease. J Urol. 2002;167:1268–1270
  22. Bachmann A, Sulser T, Jayet C, et al. Retroperitoneoscopy-assisted cryoablation of renal tumors using multiple 1.5 mm ultrathin cryoprobes: A preliminary report. Eur Urol. 2005;47:474–479
  23. Warlick CA, Lima GC, Allaf ME, et al. Clinical sequelae of radiographic ice ball involvement of collecting system during computed tomography-guided percutaneous renal tumor cryoablation. Urology. 2006;67:918–922
  24. Aron M, Gill IS. Minimally invasive nephron-sparing surgery (MINSS) for renal tumors (Part I: Laparoscopic partial nephrectomy). Eur Urol. 2007;51:337–346
  25. Ljungberg B, Alamdari FI, Rasmuson T, et al. Follow-up guidelines for nonmetastatic renal cell carcinoma based on the occurrence of metastases after radical nephrectomy. BJU Int. 1999;84:405–411
  26. Stein AJ, Mayes JM, Mouraviev V, et al. Persistent contrast enhancement several months after laparoscopic cryoablation of the small renal mass may not indicate recurrent tumor. J Endourol. 2008;22:2433–2439
  27. Hasan W, Gill IS, Spaliviero M, et al. Renal cryoablation: 4-year follow-up. J Urol. 2004;171:438;[Abstract 1657].
  28. Sung GT, Gill IS, Hsu TH, et al. Effect of intentional cryo-injury to the renal collecting system. J Urol. 2003;170(2 Pt 1):619–622
  29. Janzen NK, Perry KT, Han KR, et al. The effects of intentional cryoablation and radio frequency ablation of renal tissue involving the collecting system in a porcine model. J Urol. 2005;173:1368–1374
  30. Brashears JH, Raj GV, Crisci A, et al. Renal cryoablation and radio frequency ablation: An evaluation of worst case scenarios in a porcine model. J Urol. 2005;173:2160–2165
  31. Johnson DB, Solomon SB, Su LM, et al. Defining the complications of cryoablation and radio frequency ablation of small renal tumors: A multi-institutional review. J Urol. 2004;172:874–877
  32. Gervais DA, McGovern FJ, Arellano RS, et al. Radiofrequency ablation of renal cell carcinoma, Part 1: Indications, results, and role in patient management over a 6-year period and ablation of 100 tumors. AJR Am J Roentgenol. 2005;185:64–71
  33. Shingleton WB, Sewell PE. Percutaneous renal tumor cryoablation with magnetic resonance imaging guidance. J Urol. 2001;165:773–776
  34. Hegarty NJ, Kaouk JH, Remer EM, et al. Laparoscopic renal cryoablation: Oncological outcomes at 5 years. J Endourol. 2006;20(Suppl 1):A12
  35. Davol PE, Fulmer BR, Rukstalis DB. Long-term results of cryoablation for renal cancer and complex renal masses. Urology. 2006;68(1 Suppl):2–6
  36. Cestari A, Guazzoni G, dell'Acqua V, et al. Laparoscopic cryoablation of solid renal masses: Intermediate term followup. J Urol. 2004;172(4 Pt 1):1267–1270
  37. Lawatsch EJ, Langenstroer P, Byrd GF, et al. Intermediate results of laparoscopic cryoablation in 59 patients at the Medical College of Wisconsin. J Urol. 2006;175:1225–1229
  38. Atwell TD, Farrell MA, Leibovich BC, et al. Percutaneous renal cryoablation: Experience treating 115 tumors. J Urol. 2008;179:2136–2140
  39. Bandi G, Wen CC, Hedican SP, et al. Cryoablation of small renal masses: Assessment of the outcome at one institution. BJU Int. 2007;100:798–801
  40. Veltri A, De Fazio G, Malfitana V, et al. Percutaneous US-guided rf thermal ablation for malignant renal tumors: Preliminary results in 13 patients. Eur Radiol. 2004;14:2303–2310
  41. Varkarakis IM, Allaf ME, Inagaki T, et al. Percutaneous radio frequency ablation of renal masses: Results at a 2-year mean follow-up. J Urol. 2005;174:456–460
  42. Matin SF, Ahrar K, Cadeddu JA, et al. Residual and recurrent disease following renal energy ablative therapy: A multi-institutional study. J Urol. 2006;176:1973–1977
  43. Zagoria RJ, Traver MA, Werle DM, et al. Oncologic efficacy of CT-guided percutaneous radiofrequency ablation of renal cell carcinomas. AJR Am J Roentgenol. 2007;189:429–436
  44. Breen DJ, Rutherford EE, Stedman B, et al. Management of renal tumors by image-guided radiofrequency ablation: Experience in 105 tumors. Cardiovasc Intervent Radiol. 2007;30:936–942
  45. Stern JM, Svatek R, Park S, et al. Intermediate comparison of partial nephrectomy and radiofrequency ablation for clinical T1a renal tumors. BJU Int. 2007;100:287–290
  46. Levinson AW, Su LM, Agarwal D, et al. Long-term oncological and overall outcomes of percutaneous radio frequency ablation in high risk surgical patients with a solitary small renal mass. J Urol. 2008;180:499–504
  47. Goldberg SN, Gazelle GS, Mueller PR. Thermal ablation therapy for focal malignancy: A unified approach to underlying principles, techniques, and diagnostic imaging guidance. AJR Am J Roentgenol. 2000;174:323–331
  48. Ni Y, Mulier S, Miao Y, et al. A review of the general aspects of radiofrequency ablation. Abdom Imaging. 2005;30:381–400
  49. Wissniowski TT, Hänsler J, Neureiter D, et al. Activation of tumor-specific T lymphocytes by radio-frequency ablation of the VX2 hepatoma in rabbits. Cancer Res. 2003;63:6496–6500
  50. Hoey MF, Mulier PM, Leveillee RJ, et al. Transurethral prostate ablation with saline electrode allows controlled production of larger lesions than conventional methods. J Endourol. 1997;11:279–284
  51. Zagoria RJ, Hawkins AD, Clark PE, et al. Percutaneous CT-guided radiofrequency ablation of renal neoplasms: Factors influencing success. JR Am J Roentgenol. 2004;183:201–207
  52. Boss A, Clasen S, Kuczyk M, et al. Image-guided radiofrequency ablation of renal cell carcinoma. Eur Radiol. 2007;17:725–733
  53. McAchran SE, Lesani OA, Resnick MI. Radiofrequency ablation of renal tumors: Past, present, and future. Urology. 2005;66(5 Suppl):15–22
  54. Heilbrun ME, Zagoria RJ, Garvin AJ, et al. CT-guided biopsy for the diagnosis of renal tumors before treatment with percutaneous ablation. AJR Am J Roentgenol. 2007;188:1500–1505
  55. Crowley JD, Shelton J, Iverson AJ, et al. Laparoscopic and computed tomography-guided percutaneous radiofrequency ablation of renal tissue: Acute and chronic effects in an animal model. Urology. 2001;57:976–980
  56. Boss A, Clasen S, Kuczyk M, et al. Radiofrequency ablation of renal cell carcinomas using MR imaging: Initial results. Rofo. 2005;177:1139–1145
  57. Bastide C, Garcia S, Anfossi E, et al. Histologic evaluation of radiofrequency ablation in renal cancer. Eur J Surg Oncol. 2006;32:980–983
  58. Brausi M, Castagnetti G, Gavioli M, et al. Radiofrequency (rf) ablation of renal tumors does not produce complete tumor destruction: Results of a phase II study. Eur Urol. 2004;3(Suppl):14–17
  59. Klingler HC, Marberger M, Mauermann J, et al. ‘Skipping’ is still a problem with radiofrequency ablation of small renal tumors. BJU Int. 2007;99:998–1001
  60. Anderson JK, Baker M, Jaffers O, et al. Time course of nicotinamide adenine dinucleotide diaphorase staining after renal radiofrequency ablation influences viability assessment. J Endourol. 2007;21:223–227
  61. Boss A, Martirosian P, Schraml C, et al. Morphological, contrast-enhanced, and spin labeling perfusion imaging for monitoring of relapse after rf ablation of renal cell carcinomas. Eur Radiol. 2006;16:1226–1236
  62. Hasebroock KM, Serkova NJ. Toxicity of MRI and CT contrast agents. Expert Opin Drug Metab Toxicol. 2009;5:403–416
  63. Lewin JS, Nour SG, Connell CF, et al. Phase II clinical trial of interactive MR imaging-guided interstitial radiofrequency thermal ablation of primary kidney tumors: Initial experience. Radiology. 2004;232:835–845
  64. Traver MA, Werle DM, Clark PE, et al. Oncological efficacy and factors influencing the success of CT-guided percutaneous radiofrequency ablation (RFA) on renal neoplasms. J Urol. 2006;175(Suppl):360
  65. Weizer AZ, Raj GV, O'Connell M, et al. Complications after percutaneous radiofrequency ablation of renal tumors. Urology. 2005;66:1176–1180
  66. Kam AW, Littrup PJ, Walther MM, et al. Thermal protection during percutaneous thermal ablation of renal cell carcinoma. J Vasc Interv Radiol. 2004;15:753–758
  67. Desai MM, Aron M, Gill IS. Laparoscopic partial nephrectomy vs. laparoscopic cryoablation for the small renal tumor. Urology. 2005;66(5 Suppl):23–28
  68. Raman JD, Thomas J, Lucas SM, et al. Radiofrequency ablation for T1a tumors in a solitary kidney: Promising intermediate oncologic and renal function outcomes. Can J Urol. 2008;15:3980–3985
  69. Carini M, Minervini A, Masieri L, et al. Simple enucleation for the treatment of PT1a renal cell carcinoma: Our 20-year experience. Eur Urol. 2006;50:1263–1268Discussion 1269–71
  70. Hwang JJ, Walther MM, Pautler SE, et al. Radio frequency ablation of small renal tumors: Intermediate results. J Urol. 2004;171:1814–1818
  71. Pavlovich CP, Walther MM, Choyke PL, et al. Percutaneous radio frequency ablation of small renal tumors: Initial results. J Urol. 2002;167:10–15
  72. Allaf ME, Varkarakis IM, Bhayani SB, et al. Pain control requirements for percutaneous ablation of renal tumors: Cryoablation vs. radiofrequency ablation—initial observations. Radiology. 2005;237:366–370

PII: S1078-1439(09)00190-2

doi: 10.1016/j.urolonc.2009.06.008

Urologic Oncology: Seminars and Original Investigations
Volume 28, Issue 3 , Pages 251-259 , May 2010

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