Urologic Oncology: Seminars and Original Investigations
Volume 30, Issue 1 , Pages 16-20 , January 2012

GREB1 tissue expression is associated with organ-confined prostate cancer

  • Alberto A. Antunes, M.D., Ph.D.

      Affiliations

    • Laboratory of Medical Investigation, LIM 55, Division of Urology, University of Sao Paulo Medical School, São Paulo, Brazil
    • Corresponding Author InformationCorresponding author. Tel.: 55-11–30617183; fax: 55-11–30618469
  • ,
  • Kátia R. Leite, M.D., Ph.D.

      Affiliations

    • Laboratory of Medical Investigation, LIM 55, Division of Urology, University of Sao Paulo Medical School, São Paulo, Brazil
    • Genoa Biotechnology SA, Alameda Ministro Rocha Azevedo, São Paulo, Brazil
  • ,
  • Sabrina T. Reis, Ph.D.

      Affiliations

    • Laboratory of Medical Investigation, LIM 55, Division of Urology, University of Sao Paulo Medical School, São Paulo, Brazil
  • ,
  • Juliana M. Sousa-Canavez, Ph.D.

      Affiliations

    • Genoa Biotechnology SA, Alameda Ministro Rocha Azevedo, São Paulo, Brazil
  • ,
  • Luiz H. Camara-Lopes, M.D., Ph.D.

      Affiliations

    • Genoa Biotechnology SA, Alameda Ministro Rocha Azevedo, São Paulo, Brazil
  • ,
  • Marcos F. Dall'Oglio, M.D., Ph.D.

      Affiliations

    • Laboratory of Medical Investigation, LIM 55, Division of Urology, University of Sao Paulo Medical School, São Paulo, Brazil
  • ,
  • Miguel Srougi, M.D., Ph.D.

      Affiliations

    • Laboratory of Medical Investigation, LIM 55, Division of Urology, University of Sao Paulo Medical School, São Paulo, Brazil

Received 12 August 2009 ,Revised 23 September 2009 ,Accepted 24 September 2009.

  • Image Result

    Relative expression of the four genes in the malignant prostatic tissue according to serum PSA value. Fold change in gene expression was calculated using the ΔΔCT method (QRel = 27−ΔΔCT). Results are

    Relative expression of the four genes in the malignant prostatic tissue according to serum PSA value. Fold change in gene expression was calculated using the ΔΔCT method (QRel = 27−ΔΔCT). Results are shown as a box plot with percentile values.

  • Image Result
    Relative expression of the four genes in the malignant prostatic tissue according to Gleason score. Fold change in gene expression was calculated using the ΔΔCT method (QRel = 27−ΔΔCT). Results are sh

    Relative expression of the four genes in the malignant prostatic tissue according to Gleason score. Fold change in gene expression was calculated using the ΔΔCT method (QRel = 27−ΔΔCT). Results are shown as a box plot with percentile values.

  • Image Result
    Relative expression of the four genes in the malignant prostatic tissue according to pathologic stage. Fold change in gene expression was calculated using the ΔΔCT method (QRel = 27−ΔΔCT). Results are

    Relative expression of the four genes in the malignant prostatic tissue according to pathologic stage. Fold change in gene expression was calculated using the ΔΔCT method (QRel = 27−ΔΔCT). Results are shown as a box plot with percentile values.

  • Image Result
    Relative expression of the four genes in the malignant prostatic tissue according to biochemical recurrence status. Fold change in gene expression was calculated using the ΔΔCT method (QRel = 27−ΔΔCT)

    Relative expression of the four genes in the malignant prostatic tissue according to biochemical recurrence status. Fold change in gene expression was calculated using the ΔΔCT method (QRel = 27−ΔΔCT). Results are shown as a box plot with percentile values.

 This study was supported by FAPESP (Fundação de Amparo à Pesquisa do Estado de Sao Paulo) under the protocol number 2006/56492-5.

PII: S1078-1439(09)00295-6

doi: 10.1016/j.urolonc.2009.09.014

Urologic Oncology: Seminars and Original Investigations
Volume 30, Issue 1 , Pages 16-20 , January 2012