Urologic Oncology: Seminars and Original Investigations
Volume 30, Issue 1 , Pages 16-20 , January 2012

GREB1 tissue expression is associated with organ-confined prostate cancer

  • Alberto A. Antunes, M.D., Ph.D.

      Affiliations

    • Laboratory of Medical Investigation, LIM 55, Division of Urology, University of Sao Paulo Medical School, São Paulo, Brazil
    • Corresponding Author InformationCorresponding author. Tel.: 55-11–30617183; fax: 55-11–30618469
    • ,
  • Kátia R. Leite, M.D., Ph.D.

      Affiliations

    • Laboratory of Medical Investigation, LIM 55, Division of Urology, University of Sao Paulo Medical School, São Paulo, Brazil
    • Genoa Biotechnology SA, Alameda Ministro Rocha Azevedo, São Paulo, Brazil
    • ,
  • Sabrina T. Reis, Ph.D.

      Affiliations

    • Laboratory of Medical Investigation, LIM 55, Division of Urology, University of Sao Paulo Medical School, São Paulo, Brazil
    • ,
  • Juliana M. Sousa-Canavez, Ph.D.

      Affiliations

    • Genoa Biotechnology SA, Alameda Ministro Rocha Azevedo, São Paulo, Brazil
    • ,
  • Luiz H. Camara-Lopes, M.D., Ph.D.

      Affiliations

    • Genoa Biotechnology SA, Alameda Ministro Rocha Azevedo, São Paulo, Brazil
    • ,
  • Marcos F. Dall'Oglio, M.D., Ph.D.

      Affiliations

    • Laboratory of Medical Investigation, LIM 55, Division of Urology, University of Sao Paulo Medical School, São Paulo, Brazil
    • ,
  • Miguel Srougi, M.D., Ph.D.

      Affiliations

    • Laboratory of Medical Investigation, LIM 55, Division of Urology, University of Sao Paulo Medical School, São Paulo, Brazil

Received 12 August 2009 ,Revised 23 September 2009 ,Accepted 24 September 2009.

References 

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  3. Stemmermann GN , Nomura AM , Chyou PH , et al.  A prospective comparison of prostate cancer at autopsy and as a clinical event: The Hawaii Japanese experience . Cancer Epidemiol Biomarkers Prev . 1992;1:189–193
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  9. Epstein JI , Amin M , Boccon-Gibod L , et al.  Prognostic factors and reporting of prostate carcinoma in radical prostatectomy and pelvic lymphadenectomy specimens . Scand J Urol Nephrol Suppl . 2005;216:34–63
  10. Nelson PS . Predicting prostate cancer behavior using transcript profiles . J Urol . 2004;172:S28–S32
  11. Rae JM , Johnson MD , Scheys JO , et al.  GREB 1 is a critical regulator of hormone dependent breast cancer growth . Breast Cancer Res Treat . 2005;92:141–149
  12. Rae JM , Johnson MD , Cordero KE , et al.  GREB1 is a novel androgen-regulated gene required for prostate cancer growth . Prostate . 2006;66:886–894
  13. Gery S , Sawyers CL , Agus DB , et al.  TMEFF2 is an androgen-regulated gene exhibiting antiproliferative effects in prostate cancer cells . Oncogene . 2002;21:4739–4746
  14. Abdul M , Hoosein NM . Gammopathy associated with advanced prostate carcinoma . Urol Res . 1995;23:185–188
  15. Liu W , Shen X , Yang Y , et al.  Trihydrophobin 1 is a new negative regulator of A-RAF kinase . J Biol Chem . 2004;279:10167–10175

☆ This study was supported by FAPESP (Fundação de Amparo à Pesquisa do Estado de Sao Paulo) under the protocol number 2006/56492-5.

PII: S1078-1439(09)00295-6

doi: 10.1016/j.urolonc.2009.09.014

Urologic Oncology: Seminars and Original Investigations
Volume 30, Issue 1 , Pages 16-20 , January 2012

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