Urologic Oncology: Seminars and Original Investigations
Volume 33, Issue 2, February 2015, Pages 103-104
Urologic Oncology SurveyCommentary on “Asymptomatic prostatic inflammation in men with clinical BPH and erectile dysfunction affects the positive predictive value of prostate-specific antigen.” Agnihotri S, Mittal RD, Kapoor R, Mandhani A, Department of Urology & Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.: Urol Oncol 2014; [Epub ahead of print]. doi: 10.1016/j.urolonc.2014.03.004.
Section snippets
Commentary
The authors aimed to test the hypothesis that erectile dysfunction (ED) in elderly men with benign prostatic hyperplasia (BPH) leaded to prostatic inflammation which lowered the positive predictive value of prostate-specific antigen (PSA). We agreed with their conclusion, as demonstrated by several international studies [1], [2], [3], that a considerable proportion of men with BPH had significant inflammation of the prostate, which caused spurious rise in PSA level resulting in an unnecessary
Acknowledgment
This work was supported by the National Natural Science Foundation of China (Grant no. 81270841) and Pillar Program from Science and Technology Department of Sichuan Province (Grant no. 2013SZ0034).
References (5)
- et al.
The relationship between prostate inflammation and lower urinary tract symptoms: examination of baseline data from the REDUCE trial
Eur Urol
(2008) - et al.
The impact of acute or chronic inflammation in baseline biopsy on the risk of clinical progression of BPH: results from the MTOPS study
J Urol
(2005)
There are more references available in the full text version of this article.
Cited by (0)
Copyright © 2014 Elsevier Inc. All rights reserved.